NetBackup master server is not supported on a btrfs file system
On UNIX platforms, the NetBackup Sybase database files reside on the master server in the directories at the following location: /usr/openv/db.
NetBackup does not support the database if it is installed or upgraded on a btrfs file system. For successful NetBackup operations, ensure that the NetBackup database directories are on a file system other than btrfs, for example ext4 or xfs.